JE virus is the most important cause of viral encephalitis in Asia.
Usually asymptomatic. However, when clinical disease develops, the case-fatality ratio is 20-30% and 30-50% of the survivor of severe cases will continue to have neurologic, cognitive, or psychiatric symptoms
Bite from an infected mosquito, primarily Culex species.
Worldwide annually (estimated).
Fever, chills, headache, muscle pain, mental confusion, spasms in the neck and spine, muscle weakness.
Long-term neurologic, psychosocial, intellectual and/or physical disabilities in about 30-50% of survivors of severe cases; death.
Precautions against JE, including avoiding mosquito bites and vaccination, should be considered:
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